PLB198/PBI298 Natural product chemistry

                             (2 units)    CRN: 86508 (PLB198)/ 83789 (PBI298)

 

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Fall quarter, 2003

Tuesday and Thursday 1:10-2:00 pm

 

P/NP (as PLB198) or S/U (as PBI298) grading only.

 

Instructors:

Kentaro Inoue (Pomology)

Daniel Kliebenstein (Vegetable Crops)

 

 

Date

 

Location*

Topic

Instructor

9/25

Thu

Wickson

INTRODUCTION

 

9/30

Tue

Wickson

General Introduction

KI

10/2

Thu

Wickson

Isoprenoid-1:

Biosynthetic pathway of isoprenoid

Review: Eisenreich et al. '01

KI

10/7

Tue

Wickson

Isoprenoid-2:

Carotenoid biosynthesis

Review: Sandman '01

KI

10/9

Thu

Wickson

Isoprenoid-Discussion: James' presentation

Ye et al. (2000) Engineering the Provitamin A (Beta-Carotene) Biosynthetic Pathway into (Carotenoid-Free) Rice endosperm. Science 287:303-305

JAO, JG

10/14

Tue

Wickson

Alkaloid-1

Review: Facchini '01

DJK

10/16

Thu

MU

Alkaloid-2

DJK

10/21

Tue

Wickson

Alkaloid-Discussion

Voelckel et al. (2001) Anti-sense expression of putrescine N-methyltransferase confirms defensive role of nicotine in Nicotiana sylvestris against Manduca Sexta. CHEMOECOLOGY 11 (3): 121-126

KL, RJ

10/23

Thu

Wickson

Phenylpropanoid-1

Review: Winkel-Shirley '01

KI

10/28

Tue

Wickson

Phenylpropanoid-2

KI

10/30

Thu

Wickson

Phenylpropanoid-Discussion

Bais et al. (2003) Allelopathy and exotic plant invasion: from molecules and genes to species interactions. Science 301:1377-1380

KY, CP, EE

11/4

Tue

Wickson

Glucosinolates

DJK

11/6

Thu

Wickson

Glucosinolates-Discussion (TWO PAPERS)

Kliebenstein et al. (2002) Genetic architecture of plastic methyl jasmonate responses in Arabidopsis thaliana. Genetics 161:1685-1696

Mikkelsen et al. (2003) Modulation of CYP79 genes and glucosinolate profiles in Arabidopsis by defense signaling pathways. Plant Physiol 131:298-308

MB

11/11

Tue

-

HOLIDAY

 

11/13

Thu

Wickson

1:10-3pm

General Phenolics/compounds

Lecture

Discussion

Wildermuth et al. (2001) Isochorismate synthase is required to synthesize salicylic acid for plant defence. Nature 414:562-565

Yun et al. (2003) Loss of actin cytoskeletal function and EDS1 activity, in combination, severely compromises non-host resistance in Arabidopsis against wheat powdery mildew. Plant J 34:768-777 

DJK

CJ, KSJ, MR

11/18

Tue

Wickson

Ecology and Evolution-1

DJK

11/20

Thu

MU

Ecology and Evolution-2

DJK

11/25

Tue

Wickson

Ecology and Evolution-Discussion canceled

 

11/27

Thu

-

Holiday

 

12/2

Tue

Wickson

Glycosides and Glycosidases

KI

12/4

Thu

Wickson

Discussion on Glycosides and Glycosidases

Bouarab et al. (2002) A saponin-detoxifying enzyme mediates suppression of plant defences.

Nature 418:889-892

Putalun et al. (2003) Anti-solasodine glycoside single-chain Fv antibody stimulates biosynthesis of solasodine glycoside in plants.

Plant Cell Rep 22:344-349

CH, AM

*Location: 2124 Wickson or MU Garrison Room (on Oct 16th, Nov 20th)